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CHAPTER NO





CHAPTER
NO.21
CELL
CYCLE
 
COMPLETION ITEMS.
Fill in the blanks. 


The period of divison
during cell cycle is called _______ phase.
In yeast cells,
cell cycle is completed in _______ minutes.
During cell division,
_______ sets of microtubules originate from each pair of centrioles.
The spread of tumor
cells and establishment of secondary areas of growth is called _______.
Pairing of chromosomes
starts in _______ stage of prophase-I.
In Down's syndrome,
chromosome no. _______ fails to segregarte.
Individuals with
Down's syndrome have _______ chromosomes.
A person with klinefelter's
syndrome has an extra _______ chromosome.
The persons affected
with Turner's syndrome have _______ chromosomes.
Internal programme
of events and sequence of morphological changes by which cell commits
suicide is called _______.
The cell death due
to tissue damage is called _______.
Division of the
nucleus is called _______.
The microtubules
of centrioles are made of a protein _______.
The most critical
phase of mitosis which ensures equal distribution of chromatids in the
daughter cells is called _______.
In human, S-phase
takes about _______ hours.
Mongolism is also
known as _______.
_______ phase precedes
G2 phase.
The specialized
microtuble structure including aster and spindle is called _______.
_______ is formed
from vesicles which originate from golgi complex.
_______ is the
special area of centromere where spindle fibers attach.

 
TRUE/FALSE
ITEMS.
Encircle
the correct  answer. (T  /  F) 


Interphase is the
period of great biochemical activity. (T  /  F)
Meiosis occurs in
haploid cells. (T  /  F)
During S-phase,
DNA is synthesized and chromosome number is doubled. (T 
/  F)
Division of the
cytoplasm is called cytokinesis. (T  /  F)
Equatorial plate
is formed during telophase. (T  /
F)
Pharagmoplast is
formed in plants. (T  /  F)
In mitosis the hereditary
material is equally distributed in the daughter cells. (T 
/  F)
The interphase of
meiosis lacks, G1 stage. (T  /  F)
Go stands
for no gap. (T  /  F)
Crossing over takes
place during metaphase. (T  /  F)
During diplotene,
the paired chromosomes repel each other and begin to separate.         
(T  /  F)
The chances of
teenage mother having down's syndrome child is one in many thousands.
(T  /  F)
Persons with klinefelter's
syndrome produce small testes with no sperms at ejaculation. (T 
/  F)
Autosomal non-disjunction
may occur in other than 21st chromosome. (T  / 
F)
Genetic information
remains unchanged during mitosis. (T  /  F)
In human cells,
G1 takes about 13 hours. (T  /  F)
Each kinetochore
gets four fibers each from opposite poles. (T  /  F)
Individuals with
Turner's syndrome often survive with male appearance. (T 
/  F)
During crossing
over, parental chromosomes exchange segments with erach other.        
(T  /  F)
Pairing of homologous
chromosomes is called synapse. (T  /  F)

 
MULIPLE CHOICE ITEMS.
Choose and encircle
the best possible answer. 
1. It is the period of extensive
metabolic activity:


Go   c. G2
G1   d. S


 
2. In human cell, average cell
cycle is about:


6 hours   c. 18 hours
12 hours  d. 24 hours


 
3. The period of cell cycle
between two consecutive divisions is termed as:


Prophase  c. Telephase
Metaphase  d. Interphase


 
4. The vesicles forming phargmoplast
originate during:


Prophase  c. Inter
phase
Metaphase  d. Telephase


 
5. Cancer is caused mainly by
mutations in:


Somatic cells  c. G2
stage
Sex cells  d. S-phase


 
6. The interphase of meiosis
lacks:


Go stage  c. G2
stage
G1 stage  d. S
phase


 
7. Condensation of chromosomes
reaches to its maximum during:


Leptotene  c. Diplotane
Zygotenre  d. Diakinesis


 
8. The sex chromosome complement
in individuals with klinefelter's syndrome is:


XXY   c. XXYY
Xy   d. XYYY


 
9. Mitosis is divided into:


Karyokinesis  c. Interphase
Cytokinesis  d. Both
a & b


  
10. A female lacking ovaries
and germ cells is probably affected with:


Klinefelter's
syndrome  c. Down's syndrome
Turner's syndrome  d. Haemophilia


 
11. The process of meiosis is
completed in ______ divisions:


2   c. 4
3   d. 5


 
12. The number of daughter cells
produced at the end of meiosis is:


2   c. 6
4   d. 8


 
13. Meiosis occurs in:


Viruses   c. Plants
Bacteria  d. Both plants
and animals


 
14. Small localized tumors are
called:


Benign   c. Cancer
Malign   d. Interdigitate


 
15. Reduction in the chromosome
number occurs during:


Meiosis I  c. Mitosi
Meiosis II  d. Both
a & b


 
16. Crossing over occurs during:


Leptotene  c. Pachytene
Zygotene  d. Diplotene


 
17. Chromatids start moving
towards the respective poles in:


Anaphase  c. Prophase
Metaphase  d. Diplotene


 
18. Prophase I of merosis is
further divided into _______ substages:


3   c. 5
4   d. 6


 
19. The proteins which become
activated during cytokinesis are:


Actin and myosin c. Globulin
Haemoglobin  d. Fibrin


 
20. The length of chromosomes
is:


0.25 - 0.50 um  c. 0.60
- 1.2 um
0.40 - 0.80 um  d. I
um - 3 um


MATCHING ITEMS.
Match Column
'A' with 'B' and write the correct answer in Column'C'.
1. COLUMN
'A'    COLUMN 'B'   COLUMN
'C'
a. Interphase   i. Centromere   a-
b. Mitotic spindle   ii. 4.5 hours   b-
c. Kinetochore   iii. Resting phase   c-
d. G2 phase   iv. Aster
& spindle   d-


Chromatin


 
2. COLUMN
'A'    COLUMN 'B'   COLUMN
'C'
a. Phragmoplast   i. Somatic cells   a-
b. Cancer    ii. Pachytene   b-
c. Tetrad    iii. Anaphase I   c-
d. Crossing over   iv. Plant cell   d-


Zygotene


 
3. COLUMN
'A'    COLUMN 'B'   COLUMN
'C'
a. XXY    i. Necrosis   a-
b. Cell death   ii. Turner's syndrome  b-
c. Tissue culture   iii. Klinefelter's
syndrome  c-
d. Tumor cells   iv. Mitosis    d-


Metastasis


 
4. COLUMN
'A'    COLUMN 'B'   COLUMN
'C'
a. Karyokinesis   i. Pairing    a-
b. Tubulin    ii. Division of nucleus  b-
c. Apoptosis   iii. Protein    c-
d. Synapsis   iv. Leptotene   d-


Cell suicide


 
5. COLUMN
'A'    COLUMN 'B'   COLUMN
'C'
a. Meiosis I   i. Missing X   a-
b. Malignant tumor  ii. Diplotene   b-
c. Cytokinesis   iii. Rapid division   c-
d. Turner's syndrome  iv. Cell
cleavage   d-


G1 phase


 
LABELLING ITEMS.
Draw neat labeled diagram of
the following:


Mitosis
Meiosis I
A single chromosome
throughout the cell cycle.


 
***************************************************** 
 
ANSWERS. 

COMPLETION ITEMS.
1. Mitotic   2. 90   3. 3  
4. Metastasis  5. Zygotene  6. 21
7. 47   8. X   9. 45
10. Apoptosis  11. Necrosis  12. Karyokinesis
13. Tubulin   14. Anaphase  15. 10
16. Down's Syndrome 17. S   18. Mitotic
apparatus
19. Phragmoplast  20. Kinetochore
 

TRUE/FALSE ITEMS.
1 2 3 4 5 6 7 8 9 10 11 12
T F T T F T T F T F T T  

13 14 15 16 17 18 19 20
T T T F F F T F
MULTIPLE CHOICE ITEMS.
1 2 3 4 5 6 7 8 9 10 11 12
b d d b a c d a d b a b 

13 14 15 16 17 18 19 20
d a a c a c a a 

MATCHING ITEMS.
1 a b c d  2. a b c d
      iii iv i. ii   iv i. v ii 

3. a b c d  4. a b c d
      ii i. iv v   ii iii v i. 

5. a b c d
      ii iii iv i. 

LABELLING ITEMS.